The report claimed Mr Bolsonaro made a “deliberate and conscious” decision to delay buying the vaccine, which killed 95,000 Brazilians.
The nearly 1,200-page document criticizes Mr. Bolsonaro’s anti-vaccine and anti-science rhetoric during his country’s response. coronavirus pandemic.
Mr Bolsonaro dismissed the investigation – led by opposition senator Renan Calheiros – as politically motivated.
The report said Bolsonaro was guided by “an unfounded belief in the principle of herd immunity by the existence of natural infections and remedies.”
“Without the vaccine, the deaths would be stratospheric, as they did,” the report said.
The draft report still needs to be voted on by the Senate and can be vetoed and changed. Voting is to be held next week.
In total, the report recommends 13 criminal charges against Mr Bolsonaro for a range of actions, including genocide against Brazil’s indigenous population, that left his community vulnerable to the virus.
Commentators have said it is highly unlikely he will face trial over any such charges that would have to be brought by Brazil’s prosecutor general – a presidential candidate he had appointed.
With more than 600,000 deaths, Brazil has the second highest death toll worldwide due to Covid-19, behind only the United States.
Mr Bolsonaro has been widely criticized by public health experts for railing against the lockdown, often refusing to wear a mask in public, and declaring that he has not yet been vaccinated.
He has also pushed for unproven measures for the disease, such as the anti-malarial hydroxychloroquine.
The health ministry did not immediately respond to a request for comment.