TORONTO – A new study has found that multi-system inflammatory syndrome, a rare but serious immune reaction mainly reported in children, can also occur in adults after acute COVID-19 infection. could.
A study conducted by researchers from the US Centers for Disease Control and Prevention (CDC) found that adults with multi-system inflammatory syndrome (MIS-A) “distinguishing clinical symptoms” from COVID-19 about four weeks after contracting.
These symptoms include fever, low blood pressure, abdominal pain, heart disease, shortness of breath and diarrhea.
study published in, Peer-reviewed medical journal JAMA Network Open In September, it was found that people with a multi-system inflammatory response had more severe reactions to the virus.
- Newsletter sign-up: Get the COVID-19 brief sent to your inbox
The multi-system inflammatory reaction affects about one in 1,000 children and occurs when various parts of the body – including but not limited to the heart, lungs, and skin – become inflamed.
However, the latest study shows that adults with the condition tend to be more seriously ill than children, require longer hospital stays and have a greater need for ventilation.
Researchers identified 221 patients with MIS-A by conducting a case report literature review and examining cases reported to CDC.
The mean age of the patients was 21 years, and 70 percent were male. The study also reported that black and Hispanic patients had a higher proportion of cases. According to the study, 58 percent of the participants had no underlying comorbidities.
Compared to children who developed the condition, the study reported that adult patients were more likely to have a “symptomatic COVID-19-like illness” approximately 28 days earlier, and were more likely to develop myocarditis, heart dysfunction, as well as arterial thrombosis, pulmonary edema, and pulmonary edema. were present together. Embolism, or deep venous thrombosis.
More than half of the cases (57 percent) were admitted to the intensive care unit, with 47 percent requiring respiratory support and 7 percent dying, according to the study.
The study noted that adults with MIS had an average of five organ systems affected by the condition, and an average hospital stay of eight days.
The researchers say their findings suggest that “MIS-A is a serious hyperinflammatory condition” that can cause “extrapulmonary multiorgan dysfunction” in affected adults.
However, the study authors acknowledge that MIS in adults is not well studied, and say that a better understanding, diagnosis and treatment of the condition may reduce COVID-19 morbidity and mortality.
“It is important for the clinical and public health community to suspect and identify MIS-A, a delayed immune response to SARS-CoV-2 infection in adults with hyperinflammation, using diagnostic skills. and considering empirical treatment to reduce associated morbidity and mortality.