The trial will give participants both AstraZeneca / Oxford and Pfizer / BioNTech supplements
According to a senior member of the research team, the results of a world-first study that mix and match COVID-19 vaccines are expected in the summer.
Volunteers are to be recruited for the study starting today, with more than 800 people over the age of 50 asking to be helped.
The interval between doses will be either four or 12 weeks to test whether giving the immune response more time to mature can improve results.
Matthew Snape, a vaccineologist at Oxford University and part of the Oxford Vaccine Team, told Sky News, “We want to uncontroll the trial this month and then start getting results in June or July, looking at antibody levels. Low Less than.
“This is our goal and it will be time to influence the second dose of vaccines for the rollout to occur over the next few months.”
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The study, conducted by the National Immunization Schedule Evaluation Consortium (NISEC), will be conducted at eight hospital centers around England. Volunteers will be recruited in the next two to three weeks COVID-19 Vaccine Research Registry.
They will have regular blood tests to assess their levels of antibodies and T-cells, which helps cleanse the infection and act as immune memory.
Further vaccines can also be added to the mixture once approved by the medical regulator.
Prof. Snape stated that the ability to use different jobs would be against any supply problem.
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He Said: “If we show that these vaccines can be used interchangeably on the same schedule, this will greatly increase the flexibility of vaccine delivery, and may provide clues that protection against new virus strains To increase its width. “
Minister for COVID-19 vaccine deployment Nadim Zahavi said: “This is a highly important clinical trial that will provide us with more important evidence on the safety of these vaccines when used in various ways.”
There is no current plan to change the current vaccine schedule, with a difference of up to 12 weeks between two doses of the same jab.
A consultant for communicable disease control in Public Health England, Dr. Peter English said: “Many vaccines work better if used to promote a different vaccine – an approach known as heterologous boosting.
“Examples include hepatitis B, where some people respond poorly to vaccination but preferably if given a rhombus booster.”