Pfizer COVID-19 booster effective against virus, Delta strain, company says

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Pfizer Inc and German partner BioNTech SE on Thursday said data from a Phase III trial demonstrated the high efficacy of booster doses of their COVID-19 vaccine against the virus, including the delta variant.

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He said a trial of 10,000 participants aged 16 or older showed 95.6 percent effectiveness against the diseases, during a period when the delta strain was prevalent.

The study also found that the booster shot had a favorable safety profile.

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Pfizer cites a study showing that the effectiveness of its two-shot vaccine tends to decrease over time, showing 84 percent effectiveness from a peak of 96 percent four months after the second dose. Some countries had already gone ahead with the plan to give booster doses.

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The drugmakers said the median time between the second dose and the booster shot or placebo in the study was about 11 months, adding that there were only five cases of COVID-19 in the booster group, compared with 109 cases in the group. in comparison. Placebo Shot.

“These results provide further evidence of the benefits of boosters as we aim to keep people well protected against this disease,” Pfizer CEO Albert Boerla said in a statement.

The mean age of participants was 53 years, with 55.5 percent of participants being between 16 and 55 years old, and 23.3 percent 65 years of age or older.

The companies said they would submit the detailed results of the trial for peer-reviewed publication to the US Food and Drug Administration (FDA), the European Medicines Agency and other regulatory agencies as soon as possible.

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US, EU and Canadian regulators have recommended a third dose of COVID-19 vaccines by Pfizer-BioNtech and Moderna Inc for patients with weakened immune systems who are likely to have weaker protection from the two-dose regimen.

Canada is also recommending a third dose for residents of long-term care homes and senior citizens living in other collective settings.

— With files from Granthshala News

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